The second edition of the Oral Health Atlas highlights the extent of oral diseases worldwide and reflects on policies and strategies addressing the global burden. It presents a summary of key oral health issues, including: the impact and burden of oral diseases, such as tooth decay, periodontal disease, oral cancer and more; major risk factors and the common risk factor approach; inequalities in oral health; oral disease prevention and management; oral health challenges; and ensuring oral health is on the global health and development agendas.